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Pulmonary Interstitial Emphysema
Question:
What is Pulmonary Interstitial Emphysema and who is affected by it?

Answer:
Pulmonary interstitial emphysema is the result of air pressure exerted during mechanical ventilation (a respirator). The typical patient with PIE is an infant (usually preterm) who has such severe lung disease that he or she is placed on high-pressure mechanical ventilation; some air sacs (alveoli) rupture under the pressure and air leaks into the interstitial space (the part of the lung right around the tiny blood vessels that supply the alveoli.