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Interstitial Emphysema
Question:
What is interstitial emphysema?

Answer:
Pulmonary interstitial emphysema is the result of air pressure exerted during mechanical ventilation (a respirator). The typical patient with PIE is an infant (usually preterm) who has such severe lung disease that he or she is placed on high-pressure mechanical ventilation; some air sacs (alveoli) rupture under the pressure and air leaks into the interstitial space (the part of the lung right around the tiny blood vessels that supply the alveoli. Interstitial emphysema is associated with pulmonary barotrauma rather than DCS per se, and results in bubbles inside the pleural membrane which do not enter the blood stream. Can lead to pneumothorax, or to an arterial gas embolism should the pleural membrane rupture. Emphysema and embolism are the conditions caused by bubbles, rather than the actual bubbles themselves.